ISOLASI DAN KARAKTERISASI  SENYAWA ALIFATIK TAK JENUH DARI KULTUR AKAR MORUS CATHAYANA

NI YUNIANTARI; Euis  Holisotan Hakim

doi:10.36526/jc.v7i1.4852

NI YUNIANTARI Politeknik Negeri Banyuwangi
Euis Holisotan Hakim Kelompok Keahlian Kimia Organik Bahan Alam, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Teknologi Bandung Jl. Ganesa No. 10. Coblong, Kota Bandung, Jawa Barat Indonesia 40132

DOI: https://doi.org/10.36526/jc.v7i1.4852

Keywords: Morus cathayana, unsaturated aliphatic, steroid, terpenoid

Abstract

Moraceae is a plant that is widely distributed in Asia and the Indopacific Islands. One of the genera of Moraceae that has been widely researched and whose bioactive compounds is the Morus, namely M. cathayana. the aim of this research is determining the diversity of secondary metabolite of root cultures of Morus cathayana. Isolation of secondary metabolites from Morus cathayana root cultures was using several chromatographic techniques and eluents combination is n-hexane, acetone, chloroform, ethyl acetate and methanol. In this research, the compound KMAC-4 was isolated. Characterization of the KMAC-4 compound using the FTIR ONE Perkin-Elmer spectrophotometer. showed that the KMAC-4 compound had an absorption at wave number (cm-1): 3654.97; 3650.45; 2936.87; 1718.71; 1465.76; 1381.56; 1049.50. Based on IR spectrum data that has been interpreted, analyzed and studied according to the phytochemical of the Morus, it can be concluded that the KMAC-4 is an unsaturated aliphatic compound which belongs to the steroid or terpenoid group.

References

Berg, C. C., & Moreae, A. Dorstenia (Moraceae) with introductions to the family and ficus and with additions and corrections to Flora Neotropica Monograph 7. New York: New York Botanical Garden, 2001. 346 p. Flora neotropica. Monograph, 83.
Fessenden, R. J. JS Fessenden. (1982). Organic Chemistry. 2nd. ed. Prindle: Weber & Schmidt Publishers.
Hakim, A. (2011). Keanekaragaman Metabolit Sekunder Genus Artocarpus (Moraceae). Nusantara Bioscience, 2, 146–156.
Larkin, P. (2017). Infrared and Raman spectroscopy: principles and spectral interpretation. Elsevier.
Ni, G., Zhang, Q. J., Wang, Y. H., Chen, R. Y., Zheng, Z. F., & Yu, D. Q. (2010). Chemical constituents of the stem bark of Morus cathayana. Journal of Asian Natural Products Research, 12(6), 505–515. https://doi.org/10.1080/10286020.2010.489817
Ni, G., Zhang, Q. J., Zheng, Z. F., Chen, R. Y., & Yu, D. Q. (2009). 2-Arylbenzofuran derivatives from Morus cathayana. Journal of Natural Products, 72(5), 966–968. https://doi.org/10.1021/np800789y
R, V. K., & Chauhan, S. (2008). Mulberry : Life enhancer. J. Med. Plants Res., 2(10), 271–278.
Shen, R. C., & Lin, M. (2001). Diels-Alder type adducts from Morus cathayana. Phytochemistry, 57(8), 1231–1235. https://doi.org/10.1016/S0031-9422(01)00171-6
Zerega, N. J. C., Clement, W. L., Datwyler, S. L., & Weiblen, G. D. (2005). Biogeography and divergence times in the mulberry family (Moraceae). Molecular Phylogenetics and Evolution, 37(2), 402–416. https://doi.org/10.1016/j.ympev.2005.07.004
Zhekun, Z., & Gilbert, M. G. (2003). Moraceae: Flora of China vol. 5. Flora of China Editorial Committee. St. Louis: Missouri Botanical Garden Press.